I-Colistin Sulfate Cas: 1264-72-8
Inombolo Yekhathalogu | XD92222 |
Igama lemveliso | UColistin Sulfate |
CAS | 1264-72-8 |
Ifomu yemolekyulila | I-C52H98N16O13 |
Ubunzima beMolekyuli | 1155.43 |
Iinkcukacha zokuGcina | 2 ukuya ku-8 °C |
IKhowudi yoMrhumo eHarmonized | 29419000 |
Ukucaciswa kweMveliso
Imbonakalo | Mhlophe ukuya phantse kumgubo omhlophe |
uAsay | 99% imizuzu |
pH | 4-6 |
Ilahleko ekomisweni | <3.5% |
Ukunyibilika | Inyibilika simahla emanzini, inyibilika kancinane kwi-ethanol (96%), ayinyibiliki kwi-acetone trichloromethane okanye i-diethyl ether. |
Sulfate | 16 - 18% |
Ukujikeleza okuthe ngqo | -63 ukuya -73 |
Ukungcola ngokupheleleyo | <23% |
Uthuthu olufakwe emanzini | <1% |
Amandla (isiseko esomileyo) | >19000u/mg |
I-1.Iyi-antibiotics ye-peptide esisiseko, ngokukodwa kuthintelo kunye nonyango lwezifo ezithintekayo kunye nokukhuthaza ukukhula kwezilwanyana.
2.Inokudityaniswa ne-cell membrane lipoprotein phosphate free, yenza i-cell membrane surface tension iyancipha, i-permeability yanda, okubangelwa ukuphuma kwe-cytoplasm yokufa kweseli.
3.Inempembelelo enamandla yokuthintela kwiibhaktheriya zegram-negative (ingakumbi i-E. coli, i-Salmonella, i-Pseudomonas aeruginosa, i-Proteus ne-Haemophilus, njl. umngundo.
4. I-Colistin sulfate yomlomo inzima ukuyifunxa, ingenatyhefu, kulula ukubangela iintsalela zamachiza, kulula ukuvelisa ukuxhathisa iziyobisi.
Vala