I-Curcumin CAS: 458-37-7 99% Umgubo obomvu we-Orange
| Inombolo Yekhathalogu | XD90501 |
| Igama lemveliso | I-Curcumin |
| CAS | 458-37-7 |
| Ifomula yeemolekyuli | [HOC6H3(OCH3)CH=CHCO]2CH2 |
| Ubunzima beMolekyuli | 368.39 |
| Iinkcukacha zokuGcina | I-Ambient |
| IKhowudi yoMrhumo eHarmonized | 3212900000 |
Ukucaciswa kweMveliso
| Imbonakalo | Umgubo obomvu we-Orenji |
| Isivavanyi | >99% |
| Indawo yokunyibilika | 174-183°C |
| Iintsimbi ezinzima | 10ppm max |
| Ilahleko ekomisweni | 1.0% ubukhulu |
| Izinyibilikisi ezishiyekileyo | 20ppm max |
Iifilimu ze-Mucoadhesive eziqulethe i-curcumin-loaded nanoparticles zaphuhliswa, zijolise ekwandiseni ixesha lokuhlala kwifom ye-dosage kwi-cavity yomlomo kunye nokwandisa ukuxutywa kweziyobisi nge-buccal mucosa.Iifilimu zalungiswa ngendlela yokuphosa emva kokufakwa kwe-curcumin-elayishiwe i-chitosan-coated polycaprolactone nanoparticles kwi-plasticized chitosan solutions.Iindidi ezahlukeneyo ze-molar ze-mucoadhesive polysaccharide chitosan kunye nokugxilwa kwe-plasticizer glycerol zisetyenziselwe ukulungelelanisa iimeko zokulungiselela.Iifilimu ezifunyenwe kusetyenziswa i-chitosan ye-molar ephakathi kunye nephezulu ifunyenwe i-homogeneous kwaye iguquguqukayo.I-Curcumin-loaded nanoparticles yahanjiswa ngokufanayo kwifilimu, njengoko kubonakaliswe yi-atomic force microscopy kunye ne-high-resolution field-emission gun scanning electron microscopy (FEG-SEM) imifanekiso.Uhlalutyo lwamacandelo anqamlezayo efilimu usebenzisa i-FEG-SEM ibonisa ubukho be-nanoparticles ngaphakathi kweefilimu.Ukongeza, iifilimu zibonakalise ukuba zinesantya esilungileyo se-hydration kwisisombululo samathe esifanisiweyo, ebonisa ukudumba okuphezulu malunga ne-80% kunye ne-vitro elawulwa ixesha elide lokuhanjiswa kwe-curcumin.Ezi ziphumo zibonisa ukuba iifilimu ze-mucoadhesive eziqukethe i-nanoparticles zinika indlela ethembisayo yokuhanjiswa kwe-buccal ye-curcumin, enokuthi ibe luncedo ngakumbi kunyango lwezifo ze-periodontal ezifuna ukuhanjiswa kweziyobisi okuqhubekayo.© 2014 Wiley Periodicals, Inc. kunye ne-American Pharmacists Association.
