Iimveliso

I-D-erythro-Hexonic acid, 2,4,6-trideoxy-3,5-O-(1-methylethylidene)-6- [(5-methyl-1,3,4-thiadiazol-2-yl)sulfonyl]- , I-1,1-dimethylethyl ester, eyaziwa ngokuba yi-2,4,6-trideoxy-3-keto-L-lyxo-hexonic acid tert-butyl ester, i-chemical compound enesakhiwo esiyinkimbinkimbi kunye namaqela amaninzi asebenzayo.Le khompawundi inezicelo ezahlukeneyo kwiinkalo ezifana namayeza, iikhemikhali ze-agrochemicals, kunye ne-organic synthesis.Kwishishini lamachiza, le khompawundi ingasetyenziswa njengendawo ephakathi okanye yokwakha ukudibanisa abaviwa abanokuba ngamachiza.Ubume bayo obukhethekileyo beekhemikhali, kubandakanywa ne-thiadiazole kunye namaqela e-sulfonyl, inika amathuba okuphuhliswa kweeamolekyu zenoveli kunye nemisebenzi enokubakho ye-pharmacological.Abaphandi banokuguqula le ngqungquthela ukuba bazise abaxhasi abathile okanye amaqela asebenzayo, ngenjongo yokuyila abaviwa beziyobisi kunye nokuphucula amandla, ukukhetha, okanye ukuzinza kwe-metabolic.Ukongezelela, iqela le-tert-butyl ester lisebenza njengeqela elikhuselayo ekusebenzeni kwe-carboxylic acid ngexesha lokuguqulwa kokwenziwa.Olu khuseleko luqinisekisa ukuba ukusebenza kwe-asidi kuhlala kuhambelana ngexesha lokuphendula kweekhemikhali ezahlukeneyo, ukuvumela ukuqaliswa kwezinye izilungiso ezifunwayo ngaphandle kokuchaphazela i-acid moiety.Olu phawu lubaluleke kakhulu kwiinkqubo ze-multi-step synthesis, apho amanye amaqela asebenzayo anokufuna ukuba aqhutywe ngokuzimeleyo.Kwintsimi ye-agrochemicals, i-D-erythro-Hexonic acid, i-2,4,6-trideoxy-3,5-O- (1-methylethylidene)-6-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfonyl]-, 1,1-dimethylethyl ester inokusetyenziswa njengesiqalo sophuhliso lokhuseleko lwezityalo. iiarhente.Ubume bayo obukhethekileyo bunokuvumela ukuyilwa kwezinto ezintsha ezinemisebenzi ethile echasene nezitshabalalisi, ukhula, okanye izifo zezityalo.Ngokuqhubeka nokuguqulwa kunye nokuphucula, le khompawundi inokufaka isandla ekuqulunqweni kwezisombululo ze-agrochemical ezisebenzayo kunye nokusingqongileyo.Kwi-organic synthesis, le khompawundi ingaqeshwa njenge-reagent eguquguqukayo yokudala iimolekyuli ezinzima.Amaqela e-thiadiazole kunye ne-sulfonyl anikezela ngamathuba okuguqulwa kweekhemikhali ezahlukeneyo, okwenza ukuba kufakwe amaqela asebenzayo okongezelelweyo okanye ukwakhiwa kwezinye iinkqubo zendandatho.Ukuguquguquka kwayo kwesakhiwo kwenza ukuba kubaluleke kakhulu ukuhlanganiswa kweemveliso zendalo, i-pharmaceutical intermediates, okanye ezinye izinto ezixabisekileyo zezinto eziphilayo.Kubalulekile ukuba uqaphele ukuba izicelo ezithile kunye nokusetyenziswa kwe-D-erythro-Hexonic acid, i-2,4,6-trideoxy-3 ,5-O-(1-methylethylidene)-6-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfonyl]-, i-1,1-dimethylethyl ester ingahluka ngokuxhomekeke kwinjongo ekujoliswe kuyo, ekujoliswe kuyo. ikhompawundi, kunye neemeko zokusabela.Izazinzulu kunye neekhemisti kwizifundiswa, ishishini, okanye amaziko ophando anokuhlola amandla ayo ekufumaneni iziyobisi, uphuhliso lwe-agrochemical, okanye i-synthetic chemistry.Ngokufutshane, i-D-erythro-Hexonic acid, i-2,4,6-trideoxy-3,5-O- (1-methylethylidene)-6 - [(5-methyl-1,3,4-thiadiazol-2-yl) sulfonyl]-, 1,1-dimethylethyl ester i-compound eguquguqukayo kunye nezicelo kumachiza, i-agrochemicals, kunye ne-organic synthesis. .Ubume bayo obuyinkimbinkimbi kunye namaqela asebenzayo anikezela ngamathuba okuguqulwa kweekhemikhali ezahlukeneyo, okwenza kube luncedo kuphuhliso lwamachiza amatsha, izisombululo ze-agrochemical, okanye i-organic compounds ezixabisekileyo.Uphando olongezelelekileyo kunye nophononongo lunokuveza usetyenziso olongezelelweyo okanye izibonelelo zale khompawundi kuzo zonke iinkalo ezahlukeneyo zenzululwazi kunye nezoshishino.