I-Erythromycin CAS: 114-07-8 99% I-crystalline powder emhlophe
| Inombolo Yekhathalogu | XD90353 |
| Igama lemveliso | Erythromycin |
| CAS | 114-07-8 |
| Ifomula yeemolekyuli | C37H67NO13 |
| Ubunzima beMolekyuli | 733.93 |
| Iinkcukacha zokuGcina | I-Ambient |
| IKhowudi yoMrhumo eHarmonized | 29415000 |
Ukucaciswa kweMveliso
| Ukuchongwa | IR ukufunxwa spectrum uthelekiso kunye USP RS |
| Amanzi | 10% max |
| I-Ethanol | 0.5% ubukhulu |
| Intsalela kwi-Ignition | 0.2% ubukhulu |
| Isivavanyi | 99% |
| Ukujikeleza okuthe ngqo | -71 ° ukuya -78 ° |
| Imbonakalo | Umgubo omhlophe wekristale |
| Ubukhazikhazi | Uyahlangabezana neemfuno |
| Erythromycin B | 12.0% ubukhulu |
| ErythromycinC | 5.0% ubukhulu |
| Umda we-thiocyanate | 0.3% ubukhulu |
| Ipropanol | 0.5% ubukhulu |
| N-butyl acetate | 0.5% ubukhulu |
| I-Erythromycin A enol ether | 0.3% ubukhulu |
| Naziphi na izinto ezinxulumene nomntu | 3.0% ubukhulu |
Kuphononongo lwangoku, sivavanye ukusebenzisana kwee-antimicrobial agents ezinemodeli ezine ze-lipid membranes ezilinganisa i-membrane yeseli ye-mammalian kunye ne-Gram-positive kunye ne-negative ye-bacterial membranes kwaye sihlalutye i-kinetics ebophelelayo ngokusebenzisa i-surface plasmon resonance (SPR) indlela yethu.Iimpawu ezikhethiweyo kunye nezikhethekileyo zokubopha i-antimicrobial agents kwi-lipid membranes zaqikelelwa, kwaye imilinganiselo yekinetic yahlalutywa ngokusetyenziswa kwemodeli yokuphendula yamazwe amabini.Uhlalutyo olunokuphinda luveliswe kwi-kinetics ebophelelayo lwabonwa.I-Vancomyicn, i-teicoplanin, i-erythromycin, kunye ne-linezolid ibonise ukusebenzisana okuncinci kunye neembrane ezine ze-lipid kwinkqubo ye-SPR.Ngakolunye uhlangothi, i-vancomycin analogues ibonise ukusebenzisana kunye nemodeli ye-lipid membranes kwinkqubo ye-SPR.Iimpawu ezikhethiweyo kunye nezikhethekileyo zokubopha i-vancomycin analogues kwi-lipid membranes zixoxwa ngokusekelwe kwidatha ye-in vitro imisebenzi ye-antibacterial kunye nedatha yethu kwi-affinity ebophelelayo ye-D-alanyl-D-ala elithoba i-terminus yodonga lweseli ye-pentapeptide efunyenwe yi-SPR.Indlela yokusebenza kwe-antibacterial ngokuchasene ne-Staphylococcus aureus kunye ne-enterococci enganyangekiyo ye-vancomycin inokuvavanywa kusetyenziswa ubudlelwane obubophelelayo obufunyenwe ngobuchule bethu be-SPR.Iziphumo zibonisa ukuba indlela ye-SPR ingasetyenziswa ngokubanzi ukuxela kwangaphambili iimpawu zokubopha, ezifana nokukhetha kunye neenkcukacha, ezininzi ze-antimicrobial agents kwi-lipid membranes.
