Iimveliso

I-Ethyl 2-(piperidin-4-yl) butanoate hydrochloride yikhemikhali yekhemikhali ebizwa ngokuba yiCompound Y. Yityuwa ephilayo ephuma kwi-esterification yepiperidine, i-cyclic amine, kunye ne-butyric acid, elandelwa ukuguqulwa kwayo kwi-hydrochloride. ifom yetyuwa.Le khompawundi inezicelo ezahlukeneyo ezinokubakho kwiinkalo zekhemikhali yamayeza, i-pharmacology, kunye ne-organic synthesis.Enye yezinto eziphambili zokusetyenziswa kweCompound Y njengento yokuqala okanye ephakathi kwi-synthesis yamachiza amayeza.I-piperidine moiety yayo, eyinto eqhelekileyo yolwakhiwo kwiikhompawundi ezininzi zebhayoloji esebenzayo, iyenza ibe nezinto ezahlukeneyo kuphuhliso lwamachiza.Ngokuguqula isakhiwo seCompound Y, i-chemist inokwazisa amaqela ahlukeneyo asebenzayo okanye abathathi-nxaxheba ukuze benze izinto ezintsha eziphumayo kunye neempawu zonyango ezinokuthi zenziwe.I-Compound Y inokuphinda isebenze njenge-precursor ye-synthesis yezinye izinto ezincedo.Ngokomzekelo, inokusetyenziswa njengebhloko yokwakha kwi-synthesis ye-analogs ye-neurotransmitter ethile, engasetyenziselwa iinjongo zophando ukuqonda kakuhle ukusebenza kwenkqubo ye-nervous okanye njengabaviwa beziyobisi ezinokuthi zibe neengxaki ze-neurological disorders.Ngaphezu koko, iCompound Y kunye i-derivatives inokufumana izicelo njenge-anesthetics yendawo ngenxa yentsebenziswano kunye neziteshi zesodium kwiiseli zemithambo-luvo.Ngokuthintela la majelo, ezi zixhobo zinokuthintela ukuhanjiswa kweempawu zentlungu, okwenza zibe luncedo kwiinkqubo zokuhlinzwa okanye ukulawula intlungu.Abaphandi banokuhlolisisa ukuguqulwa kweCompound Y ukuphucula amandla ayo, ubude besenzo, kunye nokukhetha kwiintlobo ezithile zentlungu.Ukongezelela, ubukho beqela le-ester kwiCompound Y yenza kube lula kwi-hydrolysis, ukunika ithuba lokusebenzisa le ngqungquthela njenge imveliso.Iimveliso zingasebenzi okanye zingasebenzi kakuhle iikhompawundi eziguqulwa zibe yifomu yazo esebenzayo emzimbeni.Ngokuyila i-derivatives ye-Compound Y ezinzileyo kodwa inokuguqulwa ngokufanelekileyo ibe ngamachiza asebenzayo ngokusebenzisa i-enzymatic okanye i-chemical hydrolysis, izazinzulu zinokuphucula ukuhanjiswa kweziyobisi kunye nokusebenza konyango. I-Compound Y, inezicelo ezininzi kwi-chemistry yamayeza kunye ne-organic synthesis.Ukuguquguquka kwayo njengekhompawundi ephakathi ivumela ukuhlanganiswa kweemolekyuli ezahlukeneyo zebhayoloji, iyenza ixabiseke kuphuhliso lwamachiza nakuphando.Ukongeza, amandla ayo njenge-anesthetic yasekhaya kunye neprodrug yandisa ngakumbi uluhlu lwayo lwezicelo.Uphando oluqhubekayo kunye nokuphononongwa kweCompound Y kunokukhokelela ekuphuhlisweni kwamachiza anoveli, ii-arhente zonyango, kunye nezixhobo zophando kwishishini lamachiza nangaphaya.