Iodoacetamide Cas: 144-48-9 98% Mhlophe ukuya kumthubi
Inombolo Yekhathalogu | XD90247 |
Igama lemveliso | Iodoacetamide |
CAS | 144-48-9 |
Ifomula yeemolekyuli | C2H4INO |
Ubunzima beMolekyuli | 184.96 |
Iinkcukacha zokuGcina | I-Ambient |
IKhowudi yoMrhumo eHarmonized | 29241900 |
Ukucaciswa kweMveliso
Ilahleko ekomisweni | <1% |
Isivavanyi | ≥98% |
Nitrogen | 7.2 - 7.8% |
Imbonakalo | Okuqinileyo okumhlophe ukuya kumthubi |
Ukunyibilika kwi-methanol | Phantse elubala |
Uhlalutyo lwe-Elemental Carbon | 12.5 - 13.2% |
I-α-Iodoacetamide yikhompawundi esetyenziswa njenge-electrophile yokuguqulwa kwe-covalent ye-nucleophilic residues kwiiprotheni (i-cysteine, i-methionine, i-histidine).Xa kulungiswa iintsalela zesayithi ezisebenzayo ze-cysteine proteases, i-α-Iodoacetamide isebenza njenge-inhibitor engenakuguquleka yale enzyme.
Ukusetyenziswa: Ingasetyenziswa njenge-protease inhibitor CH2ICONH2.Njenge-iodoacetic acid, inokuthintela ngokungenakuguquleka ii-enzymes ze-SH ngokusabela kulandelayo.R-SH+ICH2CONH2→RS-CH2CONH2+HI
Ukusetyenziswa: I-Alkylation reagents ye-histidine kunye ne-cysteine kwi-proteomics, ngokulandelelana kwe-peptide kunye ne-enzyme inhibitors.Ikwasetyenziswa kwi-organic synthesis.