L-Alanine CAS: 56-41-7 99% I-crystalline powder emhlophe
| Inombolo Yekhathalogu | XD90326 |
| Igama lemveliso | D-Alanine |
| CAS | 338-69-2 |
| Ifomula yeemolekyuli | C3H7NO2 |
| Ubunzima beMolekyuli | 89.09 |
| Iinkcukacha zokuGcina | I-Ambient |
| IKhowudi yoMrhumo eHarmonized | 29224985 |
Ukucaciswa kweMveliso
| Imbonakalo | Umgubo omhlophe wekristale |
| Isivavanyi | 98.5 - 101.5% |
| Ukujikeleza okuthe ngqo | +13,7 ukuya +15,1 |
| Iintsimbi ezinzima | <0.0015% |
| pH | 5.5 - 7 |
| SO4 | <0.03% |
| Ilahleko ekomisweni | <0.2% |
| Intsimbi | <0.003% |
| Intsalela kwi-Ignition | <0.15% |
| Ubungakanani beNcam | 200um |
| Cl | <0.05% |
| Inqanaba lezinto ezingcolisayo eziphilayo | Akukho zingcolisi |
I-γ-Glutamyltranspeptidases (γ-GTs) iqhawula i-γ-glutamyl amide bond ye-glutathione kwaye idlulisele iqela elikhutshiweyo le-γ-glutamyl kumanzi (i-hydrolysis) okanye i-amino acids eyamkelekileyo (transpeptidation).Ezi enzymes zifumaneka kuyo yonke indawo zidlala indima ephambili kwi-biosynthesis kunye nokuthotywa kwe-glutathione, kunye ne-xenobiotic detoxification.Apha sixela i-3Å isisombululo sekristale isakhiwo se-Bacillus licheniformis γ-GT (BlGT) kunye neso bunzima bayo kunye ne-l-Glu.Ulwakhiwo lweX-reyi luqinisekisa ukuba i-BlGT yeye-N-terminal nucleophilic hydrolase superfamily kwaye ityhila ukuba iproteni inendawo evulekileyo ecandekileyo ecandekileyo efana naleyo ibixelwe kwi-enzyme ye-homologous evela kwi-Bacillus subtilis, kodwa yahlukile kwezo zijongwe ngabantu γ-GT kunye ye-γ-GTs evela kwezinye ii-microorganisms.Idatha icebisa ukuba ukubophelela kwe-l-Glu kubangela ukucwangciswa kwakhona kwe-C-terminal umsila we-BlGT enkulu kunye nokuvumela ukuchongwa kweqela leentsalela ze-asidi ezinokuthi zibandakanyeke ekuqapheliseni i-ion yensimbi.Indima yezi ntsalela kuzinzo oluhambelanayo lwe-BlGT iye yaphononongwa ngokubonakalisa i-autoprocessing, umsebenzi we-enzymatic, iikhemikhali kunye ne-thermal denaturation ye-Ala enye entsha eguqulweyo.Iziphumo zibonisa ukuba ukutshintshwa kwe-Asp568 nge-Ala kuchaphazela ukusetyenzwa ngokuzenzekelayo kunye nozinzo lweprotheyini.
