![Methyl 4-(4-Fluorophenyl)-6-Isopropyl-2-[(N-methyl-N-methylsulfonyl)amino]pyrimidine-5-carboxylate(Z6)CAS: 289042-11-1 Umfanekiso ofakiweyo](http://cdn.globalso.com/xdbiochems/白色粉末2133.jpg)
![I-Methyl 4-(4-Fluorophenyl)-6-Isopropyl-2-[(N-methyl-N-methylsulfonyl)amino]pyrimidine-5-carboxylate(Z6)CAS: 289042-11-1](http://cdn.globalso.com/xdbiochems/粉末242.jpg)
I-Methyl 4-(4-Fluorophenyl)-6-Isopropyl-2-[(N-methyl-N-methylsulfonyl)amino]pyrimidine-5-carboxylate(Z6)CAS: 289042-11-1
| Inombolo Yekhathalogu | XD93411 |
| Igama lemveliso | I-Methyl 4-(4-Fluorophenyl) -6-Isopropyl-2-[(N-methyl-N-methylsulfonyl)amino]pyrimidine-5-carboxylate(Z6) |
| CAS | 289042-11-1 |
| Ifomu yemolekyulila | I-C17H20FN3O4S |
| Ubunzima beMolekyuli | 381.42 |
| Iinkcukacha zokuGcina | I-Ambient |
Ukucaciswa kweMveliso
| Imbonakalo | Umgubo omhlophe |
| uAsay | 99% imizuzu |
I-Methyl 4-(4-Fluorophenyl) -6-Isopropyl-2-[(N-methyl-N-methylsulfonyl)amino]pyrimidine-5-carboxylate, eyaziwa ngokuba yi-Z6, i-compound eneendlela ezahlukeneyo zokusebenza kwintsimi yamachiza. .Ubukho beqela le-fluoro-substituted phenyl elidityaniswe kwiring ye-pyrimidine licebisa ukuba i-Z6 inokunxibelelana neethagethi zebhayoloji, iyenze ibe ngumviwa othembisayo wemizamo yokufumanisa iziyobisi.Ukufakwa kweqela le-isopropyl kuphucula i-hydrophobicity ye-compound, enokuthi iphucule ukukwazi ukungena kwi-membrane yezinto eziphilayo kunye nokufikelela kwindawo ekujoliswe kuyo.Enye into ebalulekileyo ye-Z6 ubukho beqela le-amino le-N-methyl-N-methylsulfonyl.Eli qela lisebenzayo liye lanxulunyaniswa nokuphucula uzinzo lwe-metabolic kunye nokunciphisa iziphumo ezinokuthi zibe khona ekujoliswe kuzo.Inokuba negalelo kunyibiliko lwekhompawundi kwindawo ezingqongileyo.Ezi zakhiwo zinokuba luncedo ekuphuhliseni i-bioactive compounds.Ubukho beqela le-methyl ester kwi-Z6 linika umlinganiselo wokuzinza kunye nokulula ukuphatha.Ukongezelela, iqela le-carboxylate kwindawo ye-5 yendandatho ye-pyrimidine inokusebenza njengendawo enokwenzeka yokuguqulwa kweekhemikhali, evumela ukuba izifundo zobudlelwane bobudlelwane besakhiwo kunye nokulungiswa kweempawu ze-pharmacological. isithako (API) kunyango lwezifo ezahlukeneyo.Inokuphononongwa ngamandla ayo njenge-agent echasayo, i-antiviral drug, okanye kunyango lomhlaza.Ukudibanisa okukhethekileyo kwamaqela asebenzayo kunokubonelela ngamathuba okusebenzisana kwezinto eziphilayo ezikhethiweyo, okwenza kube ngumviwa onomdla wokumodareyithwa kwethagethi yeziyobisi.Ngaphezu koko, ubunzima besakhiwo se-Z6 kunye nokuhlukahluka kwenza kube yinto yokuqala enomdla yokuphuhliswa kwamathala eencwadi amancinci okanye i-scaffolds yeekhemikhali.Ingasebenza njengebhloko yesakhiwo sokudityaniswa kwezinto eziphuma kulwakhiwo ezahlukeneyo, okwenza kube lula ukuphononongwa kobudlelwane bomsebenzi wesakhiwo kunye nokuchongwa kweekhompawundi ezikhokelayo ukuze kuphuculwe ngakumbi.Ekuqukumbeleni, i-Z6, eneempawu zayo ezahlukileyo kunye namaqela asebenzayo, ibambe isithembiso izicelo ezahlukeneyo zamayeza.Ukubanakho kwayo njenge-API, kudityaniswa nokuguquguquka okuza kuguqulwa kunye nokulungiswa, kuyenza ibe yikhompawundi enika umdla yokufunyanwa kweziyobisi kunye neenzame zophuhliso.Uphononongo olongezelelweyo kunye nophando luyimfuneko ukuze uphonononge ngokupheleleyo kwaye usebenzise amandla alo onyango.
