I-N- Acetyl -L-cysteine CAS: 616-91-1 98% I-crystalline powder emhlophe
| Inombolo Yekhathalogu | XD90127 |
| Igama lemveliso | N - Acetyl -L-cysteine |
| CAS | 616-91-1 |
| Ifomula yeemolekyuli | C5H9NO3S |
| Ubunzima beMolekyuli | 163.1949 |
| Iinkcukacha zokuGcina | 2 ukuya ku-8 °C |
| IKhowudi yoMrhumo eHarmonized | 29309016 |
Ukucaciswa kweMveliso
| Indawo yokunyibilika | 106-112°C |
| Ukujikeleza okuthe ngqo | +21°-+25° |
| Iintsimbi ezinzima | <10ppm |
| Arsenic | <1ppm |
| pH | 2.0-2.8 |
| Ilahleko ekomisweni | ubuninzi 1.0% |
| Sulfate | <0.03% |
| Isivavanyi | 98% imizuzu |
| Intsimbi | <20ppm |
| Intsalela kwi-Ignition | ubuninzi .5% |
| Ammonium | <0.02% |
| cl | <0.04% |
| Imbonakalo | Umgubo omhlophe wekristale |
| Imeko yesisombululo | >98% |
I-N-Acetyl-L-cysteine i-amino acid e-acetylated ene-antioxidant kunye ne-mucolytic properties.Le misebenzi mibini ibonise ukuba i-N-Acetyl-L-cysteine ibaluleke kakhulu kunyango lwekhemikhali ye-cystic fibrosis, apho i-antioxidant / isimilo sokunciphisa sekhompawundi siphucula isimo sokungalingani kwenkqubo ye-redox ye-CF kunye neempawu ze-mucolytic zekhompawundi zithintela ukuxinana kunye nokudumba okuhambelana nale meko ye-redox.Njenge-mucolytic, i-N-Acetyl-L-cysteine isebenza ukutshabalalisa iibhondi ze-disulfide kwii-mucoprotein, ukukhulula kunye nokucoca i-viscosity yesikhohlela.I-N-Acetyl-L-cysteine ibonisa isenzo esincomekayo kwi-glutathione, zombini ibonisa umsebenzi we-antioxidant ngokusebenzisa i-thiol yabo yokusebenza, kwaye zombini ziboniswa ukukhusela uxinzelelo lwe-peroxidative olunxulumene nokutshatyalaliswa kwe-septic.I-N-Acetyl-L-cysteine iphinde yaboniswa ukuba ibangele i-apoptosis kwiiseli ze-vascular smooth muscle, ebonisa ukuba ezi seli ziphendula ngokuhlukileyo kwiinguqu zokunciphisa-imeko ye-oxidation kunezinye izicubu ezihlala zikhuselwe kubukho be-antioxidants.Oku kulungelelaniswa okumangalisayo kwiiseli ze-vascular smooth muscle kubonisa i-N-Acetyl-L-cysteine njengongenelelo oluthembisayo kwi-arteriosclerotic proliferation yezi seli.
Iipropati zeMichiza: I-N-acetyl-L-cysteine emhlophe i-crystalline powder, enevumba elifana negalikhi kunye nencasa emuncu.I-Hygroscopic, i-soluble emanzini okanye i-ethanol, i-ether kunye ne-chloroform.Ineasidi kwisisombululo esinamanzi (pH2-2.75 kwi-10g/LH2O), mp101-107℃Chemicalbook.Le mveliso yi-N-acetylated derivative ye-cysteine.Imolekyuli iqulethe iqela le-sulfhydryl, elinokwaphula i-disulfide bond (-SS-) yebhondi ye-mucin peptide, ngaloo ndlela ijika ikhonkco le-mucin libe yitsheyini encinci ye-peptide ye-molecular, ukunciphisa Ngenxa ye-viscosity ye-mucin, le mveliso iyanyibilika. iyeza lesikhohlela esine-viscous, isikhohlela esibuhlaza kunye nemifinya yokuphefumla.
intsebenziswano yamayeza:
1. Akufunekanga isetyenziswe kunye ne-penicillin, i-cephalosporin kunye ne-tetracycline antibiotics, njengoko le yokugqibela inokuthi ingasebenzi.
2. Ukudibanisa okanye ukusetyenziswa okunye kunye ne-isoproterenol kunokuphucula umphumo wonyango kunye nokunciphisa ukusabela okubi.
3. Kuphephe ukudibana nentsimbi kunye nezixhobo zerabha, i-oxidants, kunye neoksijini.
Ukusetyenziswa: ii-reagents zebhayoloji, izinto eziluhlaza, i-thiol (-SH) kwi-molecule inokwaphula i-disulfide chain (-SS) edibanisa ikhonkco ye-mucin peptide kwi-mucous phlegm.I-Mucin ijika i-Chemicalbook ibe yitsheyini encinci ye-peptide ye-molecular, enciphisa i-viscosity ye-sputum;inokuphinda iphule imicu ye-DNA kwi-sputum ye-purulent, ngoko ayikwazi nje ukunyibilikisa isikhohlela esimhlophe esimhlophe kodwa kunye ne-sputum e-purulent.
Ukusetyenziswa: Kwezamayeza, isetyenziswa njengechiza lokunyibilikisa i-phlegm.Kuphando lwe-biochemical, isetyenziswe njenge-antidote yokuchithwa kwe-phlegm kunye ne-acetaminophen poisoning kumayeza.
Ukusetyenziswa: Kuphando lwe-biochemical, kumayeza, isetyenziswa njengeyeza lokunyibilikisa i-phlegm kunye ne-antidote ye-acetaminophen poisoning.
Ukusetyenziswa: Ama-reagents e-Biochemical, amayeza, le mveliso isetyenziswe njenge-expectorant, ekuthiwa kulula ukuyicoca i-phlegm kwaye kulula ukukhwehlela.Inomphumela wokubola kwisikhohlela se-viscous.Indlela yokusebenza kukuba iqela le-sulfhydryl eliqulethwe kulwakhiwo lwemolekyuli yale mveliso linokwaphula ibhondi ye-disulfide I-Chemicalbook kwikhonkco le-mucin polypeptide kwi-sputum ye-mucous, ibolise i-mucin, inciphise i-viscosity yesikhohlela, kwaye iyenze ibemanzi kwaye kulula khohlela phezulu.Ifanelekile kwizifo ezibukhali nezingapheliyo zokuphefumla ezinezikhohlela ezingqindilili kwaye kunzima ukuzilindela, kunye neempawu ezibukhali zobunzima bokufunxa ngenxa yokuphazamiseka komthamo omkhulu wephlegm encangathi.
Ukusetyenziswa: I-N-acetyl-L-cysteine inokusetyenziswa njengechiza lokuchitha i-phlegm.Ifanelekile ukuthintela ukuphefumla okubangelwa ubuninzi be-phlegm enamathelayo.Ukongeza, ingasetyenziselwa ukukhutshwa kwetyhefu ye-acetaminophen.Ngenxa yokuba le mveliso inevumba elikhethekileyo, ukuyithatha kunokubangela isicaphucaphu kunye nokuhlanza ngokulula.Inomphumela ovuselelayo kwindlela yokuphefumula kwaye ingabangela i-bronchospasm.Isetyenziswa ngokudityaniswa neebronchodilators ezifana ne-isoproterenol kunye nesixhobo sokufunxa isikhohlela ukukhupha isikhohlela.Akufanele idibane neentsimbi (ezifana ne-Fe, Cu), i-rubber, i-oxidants, njl. Akufanele isetyenziswe kunye ne-antibiotics efana ne-penicillin, i-cephalosporin, i-tetracycline, njl., ukwenzela ukuba inganciphisi i-antibacterial effect.Sebenzisa ngokuqaphela kwizigulane ezine-asthma ye-bronchial.
