I-Niacinamide Cas: 98-92-0
| Inombolo Yekhathalogu | XD91246 |
| Igama lemveliso | Niacinamide |
| CAS | 98-92-0 |
| Ifomu yemolekyulila | I-C6H6N2O |
| Ubunzima beMolekyuli | 122.12 |
| Iinkcukacha zokuGcina | I-Ambient |
| IKhowudi yoMrhumo eHarmonized | 29362900 |
Ukucaciswa kweMveliso
| Imbonakalo | Imhlophe okanye iphantse imhlophe i-crystalline powder okanye ikristale engenambala |
| uAsay | ≥99% |
| Indawo yokunyibilika | 128°C ~ 131°C |
| Ukuchongwa | Okuhle |
| pH | 6.0 ~ 7.5 |
| Ilahleko ekomisweni | ≤0.5% |
| Uthuthu lweSulfate | ≤0.1% |
| Ukucaca kwesisombululo | Cacileyo |
| Intsimbi enzima | ≤0.003% |
| Umbala wesisombululo | ≤BY7 |
I-Niacinamide ikwabizwa ngokuba yi-nicotinamide, ivithamin B3, okanye ivithamin PP, luhlobo lweevithamini ezinyibilikayo emanzini, zezevithamini B, njenge-coenzyme Ⅰ, nicotinamide adenine dinucleotide (NAD) kunye ne-coenzyme Ⅱ (nicotinamide adenine dinucleotide phosphate, NADP) Kwisakhiwo somzimba womntu ezi ntlobo zimbini ze-coenzyme nicotinamide inxalenye ye-hydrogenation kunye ne-dehydrogenation iipropathi ezibuyiselwa umva, Idlala indima yokudlulisela i-hydrogen kwi-biooxidation kwaye inokukhuthaza ukuphefumla kwezicubu, inkqubo ye-biooxidation kunye ne-metabolism, ebaluleke kakhulu ekugcineni ingqibelelo. izicubu eziqhelekileyo, ngakumbi ulusu, umgudu wokugaya ukutya kunye nenkqubo ye-nervous.Xa kungabikho, ukuphefumla kunye ne-metabolism yeeseli zichaphazelekayo kwaye i-pellagra ibangelwa, ngoko ke le mveliso isetyenziselwa ukuthintela kunye nokunyangwa kwe-pellagra, stomatitis, glossitis kunye nokunye.
I-Niacinamide iveliswa kwizilwanyana kusetyenziswa i-niacinamide kunye ne-niacin phantsi kweemeko ezininzi ze-acoustic.I-Pellagra yenzeka xa umzimba unqongophele kwi-niacin kunye ne-nicotinamide.Ngoko ke banokunqanda i-pellagra.Badlala indima kwi-metabolism yeeprotheni kunye noshukela, ukuphucula ukutya kwabantu kunye nezilwanyana.Ukongeza kwiyeza, kodwa kunye nenani elikhulu lokutya kunye nezongezo zokutya.Umthamo wemveliso yehlabathi udlule iitoni ezingama-30,000.EJapan, i-niacinamide isetyenziselwa amayeza ama-40% kunye nezongezo zesondlo ngama-50%.Izongezo zokutya zibalelwa kwi-10%.I-Nicotinic acid kunye ne-nicotinamide azinatyhefu kwaye ubukhulu becala ziqulethwe kwisibindi sesilwanyana, izintso, igwele kunye neswekile yerayisi kwindawo yendalo.I-LD50 ye-nicotinamide ye-injection engaphantsi kwesikhumba kwiigundane yayiyi-1.7 g / kg.
Ukusetyenziswa: iyeza le-vitamin, lithatha inxaxheba kwinkqubo ye-metabolic yomzimba, esetyenziselwa ukuthintela kunye nokunyangwa kokusilela kwe-niacin njenge-pellagra.
Sebenzisa: kwiimveliso zokhathalelo lwesikhumba kunokuthintela ulusu olurhabaxa, ukugcina impilo yeeseli zolusu, ukukhuthaza ukuqaqamba kolusu.Ukusetyenziswa ekunyamekelweni kweenwele kunokukhuthaza ukujikeleza kwegazi kwe-scalp, iifollicle zeenwele ezinempilo, ukukhuthaza ukukhula kweenwele, ukuthintela ukubola.
Isicelo: Uphando lwe-Biochemical;Ukubunjwa kwezondlo kwi-tissue culture medium;Iyeza leklinikhi I-Chemicalbook liqela le-vitamin B, elisetyenziselwa ukuthintela kunye nokunyangwa kwe-pellagra, i-stomatitis, i-glossia kunye nezinye izifo.
Ukusetyenziswa: Kuyafana ne-niacin.I-soluble yamanzi ingcono kune-niacin, kodwa kulula ukwenza i-complex kunye ne-vitamin C kunye ne-agglomerate.Umthamo we-30-80 mg / kg.
Injongo: Uphando lwe-Biochemical.Isixhobo sokukhuliswa kwezicubu salungiswa.Ishishini lamachiza.
Sebenzisa: i-amide derivative ye-vitamin B3 kunye ne-PARP inhibitors.
