I-Nicotinamide Cas: 98-92-0 powder omhlophe
| Inombolo Yekhathalogu | XD90447 |
| Igama lemveliso | INicotinamide |
| CAS | 98-92-0 |
| Ifomula yeemolekyuli | I-C6H6N2O |
| Ubunzima beMolekyuli | 122.12 |
| Iinkcukacha zokuGcina | I-Ambient |
| IKhowudi yoMrhumo eHarmonized | 29362900 |
Ukucaciswa kweMveliso
| Imbonakalo | Umgubo omhlophe |
| Isivavanyi | 99% |
| Iintsimbi ezinzima | 128°C ~ 131°C |
| Ukuchongwa | Okuhle |
| pH | 6.0 ~ 7.5 |
| Ilahleko ekomisweni | ≤0.5% |
| Ukunyibilika | Iyahambelana |
| Uthuthu lweSulfate | ≤0.1% |
| Ukucaca kwesisombululo | Cacileyo |
| Intsimbi enzima | ≤0.003% |
Ngaphambili siseke ixesha elide, inkcubeko ye-3-dimensional ye-organoids evela kwizicubu zegundane (amathumbu, isisu, i-pancreas, kunye nesibindi) kunye namathumbu omntu kunye ne-pancreas.Apha sichaza iimeko ezifunekayo kwixesha elide le-3-dimensional culture of human gastric stem cells.Itekhnoloji ingasetyenziselwa ukufunda impendulo ye-epithelial kwintsholongwane ye-Helicobacter pylori.Sivelise i-organoids kwiisampuli zotyando ze-gastric corpus yomntu.Iimeko zenkcubeko zaphuhliswa ngokusekelwe kwezo zenkqubo yesisu semouse kunye namathumbu omntu.Sasebenzisa i-microinjection ukosulela i-organoids nge-H pylori.Iimpendulo ze-Epithelial zilinganiswe ngokusebenzisa i-microarray kunye ne-quantitative polymerase chain reaction analysis.Sikhulise iiseli ukusuka kwizicubu zesisu ezisempilweni, iiseli ezihlungwe zodwa, okanye izicubu zethumba.I-Organoids igcine iimpawu ezininzi zezicubu zazo ngokusekwe kwi-histology yazo, ukubonakaliswa kweziphawuli, kunye ne-euploidy.Ii-Organoids ezivela kwizicubu ezisempilweni zivakalise iimpawu zemigca emi-4 yesisu kwaye zilungelelaniswe ngokwazo kwidlala kunye neendawo zomgodi.Zinokubhekiswa ekuchazeni ngokukodwa imigca yedlala lesisu, okanye umngxuma wesisu, ngokongezwa kwe-nicotinamide kunye nokurhoxiswa kwe-WNT.Nangona i-gastric pit lineages yayineziphumo ezisezantsi kuphela kwintsholongwane ye-bacterial, i-gastric gland lineages iphakamise impendulo eyomeleleyo yokudumba.Siphuhlise inkqubo yokukhuthaza i-organoids yesisu somntu.Le nkqubo inokusetyenziselwa ukufunda usulelo lwe-H pylori kunye nezinye izifo zesisu.Copyright © 2015 AGA Institute.Ipapashwe ngu Elsevier Inc. Onke amalungelo agciniwe.
