Thiabendazole Cas: 148-79-8
| Inombolo Yekhathalogu | XD92377 |
| Igama lemveliso | Thiabendazole |
| CAS | 148-79-8 |
| Ifomu yemolekyulila | I-C10H7N3S |
| Ubunzima beMolekyuli | 201.25 |
| Iinkcukacha zokuGcina | I-Ambient |
| IKhowudi yoMrhumo eHarmonized | 29414000 |
Ukucaciswa kweMveliso
| Imbonakalo | umgubo wekristale omhlophe |
| uAsay | 99% imizuzu |
| Indawo yokunyibilika | 296-303°C |
| Amanzi | <0.5% |
I-Thiabendazole lichiza le-benzimidazole elaziswa njengechiza lonyango lwezilwanyana ngeminyaka yoo-1960 kwaye kamva njengechiza lomntu le-anthelminthic.Inomsebenzi obanzi we-anthelminthic osebenzayo ngokuchasene neentlobo ezahlukeneyo zosulelo lwe-nematode.Zombini i-ovicidal kunye ne-larvicidal.Ikwasebenza kakhulu ngokuchasene ne-saprophytic kunye ne-pathogenic fungi kwi-vitro kwaye ikwabonise i-anti-inflammatory, antipyretic kunye neempawu ze-analgesic kwizilwanyana zaselabhorethri[1].Ngokonyango, isetyenziswa ikakhulu ngokuchasene ne-Strongyloides stercoralis kunye ne-cutaneous larva migrans.
Indlela yokusebenza ayiqondwa ngokucacileyo.Kuye kwaboniswa ukuba inqanda i-mitochondrial fumurate reductase, echanekileyo kwi-helminths[2].I-Thiabendazole inokuchaphazela i-parasite microtubules, ngendlela efana naleyo ichazwe kwi-mebendazole (jonga i-Mebendazole).
