Thiamphenicol Cas: 15318-45-3
| Inombolo Yekhathalogu | XD92378 |
| Igama lemveliso | Thiamphenicol |
| CAS | 15318-45-3 |
| Ifomu yemolekyulila | I-C12H15Cl2NO5S |
| Ubunzima beMolekyuli | 356.22 |
| Iinkcukacha zokuGcina | I-Ambient |
| IKhowudi yoMrhumo eHarmonized | 29414000 |
Ukucaciswa kweMveliso
| Imbonakalo | Umgubo omhlophe wekristale |
| uAsay | 99% imizuzu |
| Indawo yokunyibilika | 163°C - 167°C |
| Iintsimbi ezinzima | ≤10ppm |
| Ilahleko ekomisweni | ≤1.0% |
| Ukujikeleza okuthe ngqo | -21 ° - 24 ° |
| I-Chloride | ≤0.02% |
I-Thiamphenicol sisibulali-zintsholongwane esine-spectrum esibanzi i-chloramphenicol, esisebenza ngakumbi kwiibhaktheriya ezi-gram-negative kune-bacteria yegram-positive.Kwiqondo lobushushu begumbi, ngumgubo omhlophe ukuya kumhlophe wekristale okanye ikristale, enokuthi ifunxe ngokukhawuleza nangokupheleleyo ngolawulo lomlomo, kwaye ikhutshiwe ikakhulu kwiprototype evela kumchamo wemetabolism.Isetyenziswa ngokweklinikhi kunyango lokuphefumla, i-urinary tract, isibindi kunye ne-gallbladder, i-typhoid kunye nolunye utyando lwamathumbu, i-gynecology kunye nosulelo lwe-ENT.Ngokukodwa kwizifo ezithambileyo zisebenza ngakumbi.Inokwakheka kweekhemikhali ezifanayo kunye nekloramphenicol.I-methyl sulfone yayo ithathe indawo ye-nitro ye-chloramphenicol, eyanciphisa ubuthi bayo, kwaye kwi-vivo umsebenzi wayo we-antibacterial yi-2.5-5 yamaxesha anamandla kune-chloramphenicol.Kwintsholongwane yegram-positive, efana ne-streptococcus pneumoniae kunye ne-hemolytic streptococcus, inefuthe elinamandla kakhulu lokulwa ne-antibacterial, ngelixa iintsholongwane zegram-negative, ezifana ne-Neisseria gonorrhoeae, i-meningococcus, i-lung Bacteroides, i-E. coli, i-Vibrio cholerae, i-Shigella ne-influenza, i-influenza ikwanayo nefuthe elinamandla le-antibacterial.Kwibhaktheriya ye-anaerobic, i-Rickettsia kunye ne-amoeba, inempembelelo ye-antibacterial kwinqanaba elithile.Inomsebenzi ofanayo we-antimicrobial kunye ne-chloramphenicol, eyona nto inqanda ukuhlanganiswa kweprotheni yebhaktiriya.Eli chiza lifunxwa ngokukhawuleza ngolawulo lomlomo, olufikelela kwincopho yoxinaniso lwegazi kwiiyure ezimbini.Isiqingatha sobomi bayo ziiyure ezi-5, ezinde kunechloramphenicol.Iibhaktheriya zinokuchasana okupheleleyo kuyo kunye ne-chloramphenicol, ngelixa iibhaktheriya zinento ethile yokumelana nayo kunye ne-tetracycline.
I-Thiamphenicol nayo ineempembelelo ezinamandla zokugonywa kwe-immunosuppressive, eyona nto igqwesileyo ye-immunosuppressant.Indlela yokusebenza kwayo ihluke kakhulu kunye nezinye i-immunosuppressive agents.Impembelelo ye-immunosuppressive ngamaxesha amaninzi aphezulu kune-chloramphenicol.Inokuba njengesandisi esisebenzayo sokusabela kwi-transplantation kunye noqhaqho lotyando lwe-allogeneic.
