I-Tiamulin fumarate Cas: 55297-96-6
| Inombolo Yekhathalogu | XD92379 |
| Igama lemveliso | I-Tiamulin fumarate |
| CAS | 55297-96-6 |
| Ifomu yemolekyulila | I-C32H51NO8S |
| Ubunzima beMolekyuli | 609.82 |
| Iinkcukacha zokuGcina | 2 ukuya ku-8 °C |
| IKhowudi yoMrhumo eHarmonized | 29419000 |
Ukucaciswa kweMveliso
| Imbonakalo | Mhlophe/ off umgubo omhlophe |
| uAsay | 99% imizuzu |
| Indawo yokunyibilika | 143 - 149°C |
| Iintsimbi ezinzima | <10ppm |
| pH | 3.1 - 4.1 |
| Ilahleko ekomisweni | <0.5% |
| Ukunyibilika | Inyibilika emanzini, inyibilika ngokukhululekileyo kwi-ethanol ene-anhydrous kwaye inyibilika kwi-methanol |
| Ukujikeleziswa kwe-Optical | +24 ukuya +28 |
| Intsalela kwi-Ignition | <0.1% |
| Ukungcola ngokupheleleyo | <2% |
| Isiqulatho samanzi (KF) | ≤ 4.0% |
I-Tiamulin yi-semi-synthetic analogue ye-pleuromutilin apho ikhonkco elisecaleni le-hydroxyacetyl litshintshwa nge-diethylaminoethylthioacetyl moiety enkulu, ebonelela nge-hydrophobicity enkulu.I-hemi-fumarate ibonelela ngetyuwa ezinzileyo enokuphuculwa kokunyibilika kwamanzi.I-Tiamulin sisibulali-zintsholongwane esinamandla kwaye sikhetha kakhulu esisebenzayo ngokuchasene noluhlu lweebhaktheriya ze-Gram positive, ngaphandle kokuchasana okunqamlezayo kwiiklasi ezikhoyo zamayeza okubulala iintsholongwane ngenxa yendlela yayo ekhethekileyo yokuthintela ukuhlanganiswa kweeprotheni ngokuzibophelela kwi-domain V ye-23S rRNA.
Vala
