Ityuwa ye-sodium ye-Ampicillin CAS: 69-52-3 99% Umgubo omhlophe okanye omhlophe
| Inombolo Yekhathalogu | XD90372 |
| Igama lemveliso | Ampicillin ityuwa yesodium |
| CAS | 69-52-3 |
| Ifomula yeemolekyuli | I-C16H18N3NaO4S |
| Ubunzima beMolekyuli | 371.39 |
| Iinkcukacha zokuGcina | 2 ukuya ku-8 °C |
| IKhowudi yoMrhumo eHarmonized | 29411000 |
Ukucaciswa kweMveliso
| Amanzi | <0.2% |
| Iintsimbi ezinzima | <20ppm |
| Isivavanyi | 99% |
| Ukujikeleziswa kwe-Optical | + 258 ° - +287 ° |
| N, N-dimethylaniline | <0.2% |
| Amandla | 845--988ug/mg (into engenamanzi) |
| Imbonakalo | Umgubo omhlophe okanye omhlophe |
Iintlobo ze-Uropathogenic ze-Escherichia coli (UPEC) ngoyena nobangela wosulelo lwe-bacteremic urinary tract.Ukusinda kwigazi kuhambelana neendlela ezahlukeneyo ezinceda ukuxhathisa ukubulawa kwe-serum complement-mediated.Ngelixa i-phenotypic heterogeneity yeebhaktheriya ibonakaliswe ukuba inefuthe ekunyamezelweni kwe-antibiotic, ukuba kunokwenzeka ukuba yenza iiseli zichase ukubulawa yi-immune system ayizange ivavanywe.Kuphononongo lwangoku siye safuna ukufumanisa ukuba i-heterogeneity yeenkcubeko zebhaktheriya ihambelana nokujoliswa kwebhaktheriya yinkqubo yokuncedisa i-serum.Sibeke iliso kwizahlulo zeeseli kwi-UPEC yoxinzelelo lwe-CFT073 kunye neprotein yentatheli ye-fluorescent.Iiseli zesigaba esimileyo zifakwe kwi-serum yomntu esebenzayo okanye engasebenziyo xa kukho okanye kungabikho kwamayeza ahlukeneyo okubulala iintsholongwane (i-ampicillin, i-norfloxacin, kunye ne-amikacin), kunye ne-cell division kunye ne-protein ehambelanayo ye-C3 yokubopha yayilinganiswa nge-flow cytometry kunye ne-immunofluorescence microscopy.I-Heterogeneity kumaxesha aphindwe kabini kwiiseli ze-CFT073 kwi-serum yenza ukuba ii-subpopulations ezintathu ze-phenotypically zihluke, zonke ziqatshelwe yi-C3 yecandelo lenkqubo yokuncedisa.Abemi beeseli ezikhula ngokukhawuleza bayaxhathisa i-serum complement-mediated lysis.Awona manani aphezulu eeseli anezinga lokukhula eliphakathi lichaphazeleka kwiserum.Abemi besithathu, abangaphinde baqalise ukukhula xa kuhlanjululwa ukusuka kwisigaba esimileyo, bakhuselwe ngaxeshanye kuncediso lweserum kunye namayeza okubulala iintsholongwane.
