Iimveliso

I-Hexafluoroisopropyl methyl ether (i-HFIPME) i-ether eguquguqukayo kunye ne-chemicals stable stable compound enoluhlu olubanzi lwezicelo kwiinkalo ezahlukeneyo.Isetyenziswa ngokuqhelekileyo njenge-solvent, i-reagent, kunye ne-agent ekhuselayo ngenxa yeempawu zayo ezizodwa.Enye yezinto eziphambili zokusetyenziswa kwe-HFIPME injenge-solvent kumashishini amachiza kunye neekhemikhali.Ukunyibilika kwayo okugqwesileyo kuzo zombini iikhompawundi ze-organic kunye ne-inorganic kuyenza ibe lolona khetho lufanelekileyo lokunyibilikisa izinto ezahlukeneyo.I-HFIPME iluncedo ngakumbi ekunyibilikiseni iikhompawundi ezinefluorinated kakhulu, iipeptides, kunye neepholima ezithile.Ikhono layo lokunyibilikisa ezi zinto zinzima zenza ukuba zixabiseke ekufumaneni iziyobisi, i-chemistry yamayeza, kunye ne-polymer synthesis.Ukongezelela kwiipropati zayo zokunyibilikisa, i-HFIPME inokusebenza njenge-reagent kwiimpendulo ezithile.Umzekelo, ingasetyenziselwa ukukhuthaza ukusabela kokuphelelwa ngamanzi emzimbeni ngokususa amanzi kwimixube yokusabela.I-HFIPME ikwanakho ukusebenza njenge-catalyst ye-Lewis acid ethambileyo, iququzelela ukusabela okwahlukeneyo okunje ngeFriedel-Crafts acylation kunye ne-cyclization reaction.Ukuphinda kusebenze kunye nokukhetha kwayo kuyenza i-reagent eguquguqukayo kwi-organic synthesis.Ngaphezu koko, i-HFIPME iyaziwa ngokukwazi ukuzinzisa i-labile compounds.Inokuthi isebenze njenge-agent ekhuselayo ukukhusela ukuthotywa okanye i-oxidation yezinto ezibucayi ngexesha lokugcina okanye iinkqubo zokuphendula.Oku kubaluleke ngakumbi ekuzinziseni abaphakathi abasebenzayo, ukukhusela amaqela asebenzayo, kunye nokugcina imfezeko yeemolekyuli ezibuthathaka.Iipropati zokuzinzisa ze-HFIPME ziyenza ixabiseke kwiinkalo zoxubo-mayeza, iikhemikhali zezolimo, kunye nenzululwazi yemathiriyeli.Ngenxa yokubilisa kwayo okuphantsi (-24.7 °C), ingasetyenziswa kwiimpendulo zobushushu obuphantsi kunye neenkqubo.Indalo ye-HFIPME ye-cryogenic iyenza ikwazi ukuqeshwa kwiinkalo ezifana ne-cryobiology, i-cryo-electron microscopy, kunye nophando lwe-superconductivity.Ukongezelela, i-HFIPME ibonise amandla kummandla wekhemikhali yohlalutyo, ngakumbi kwi-spectroscopy ye-nuclear magnetic resonance (NMR).Njengento enyibilikayo, inenani eliphantsi leproton, i-viscosity ephantsi, kunye neempawu ezibalaseleyo zokunyibilika, iyenza ibe lolona khetho lufanelekileyo kuhlalutyo lwe-NMR.I-HFIPME idla ngokukhethwa ukufunda iisampulu ezinomngeni, kubandakanywa i-peptides, iiprotheni, kunye nemveliso yendalo.Kuko konke, i-hexafluoroisopropyl methyl ether (HFIPME) iyikhompawundi eguquguqukayo kunye neentlobo ezininzi zokusetyenziswa.Iimpawu zayo zokunyibilikisa, ukusebenza kwakhona, iziphumo zokuzinzisa, indalo ye-cryogenic, kunye nokuhambelana nohlalutyo lwe-NMR lwenza ukuba luxabiseke kwiinkqubo ezahlukeneyo zesayensi kunye nezoshishino.Ukusuka kwi-pharmaceutical synthesis ukuya kwi-cryobiology, i-HFIPME idlala indima ebalulekileyo kwiinkalo ezininzi.