Iimveliso

I-Trityl candesartan lichiza elaziwa ngokuba yi-candesartan tert-butyl ester.Yikhompawundi engaphambili ye-candesartan cilexetil, esetyenziselwa ukwenza i-candesartan cilexetil.I-Candesartan cilexetil yi-angiotensin II receptor antagonist esetyenziswa ngokubanzi kunyango lwe-hypertension kunye nokusilela kwentliziyo.Isebenza ngokuthintela umsebenzi we-angiotensin II receptors, ukunciphisa uxinzelelo lwegazi, ukunciphisa umthwalo wenhliziyo, kunye nokukhuthaza i-vasodilation.Olona setyenziso luphambili lwe-Trityl candesartan kuphuhliso lwamalungiselelo amayeza luphakathi kokudityaniswa kwe-candesartan cilexetil.Isabelana nezinye izandulela ze-candesartan cilexetil ukuvelisa i-candesartan cilexetil, esetyenziswa kulungiselelo lweemveliso zoxubo mayeza.Kufuneka kuqatshelwe ukuba i-trityl candesartan ngokwayo ayilona ichiza lokugqibela lonyango, kodwa i-compound engundoqo yokulungiswa kwe-candesartan cilexetil.Ukusetyenziswa okuthe ngqo kunye nezicelo kuxhomekeke kwiimfuno zophando kunye nophuhliso lwamalungiselelo amayeza.Nawuphi na umsebenzi osebenzisa okanye ophethe imichiza kufuneka ulandele iindlela ezifanelekileyo zokhuseleko kunye nezikhokelo zelabhoratri.