Vitamin H (Biotin) Cas: 58-85-5
| Inombolo Yekhathalogu | XD91872 |
| Igama lemveliso | IVithamin H (iBiotin) |
| CAS | 58-85-5 |
| Ifomu yemolekyulila | I-C10H16N2O3S |
| Ubunzima beMolekyuli | 244.31 |
| Iinkcukacha zokuGcina | -20°C |
| IKhowudi yoMrhumo eHarmonized | 29362930 |
Ukucaciswa kweMveliso
| Imbonakalo | Umgubo omhlophe wekristale |
| uAsay | 99% imizuzu |
| Indawo yokunyibilika | 231-233 °C(lit.) |
| alpha | 89 º (c=1, 0.1N NaOH) |
| Indawo yokubilisa | 573.6±35.0 °C(Kuqikelelwe) |
| ukuxinana | 1.2693 (uqikelelo olurhabaxa) |
| isalathiso se-refractive | 90.5 ° (C=2, 0.1mol/L NaOH) |
| ukunyibilika | I-H2O: 0.2 mg / mL Ukunyibilika kwanda kunye nokongezwa kwe-1 N NaOH. |
| pka | 4.74±0.10(Kuqikelelwe) |
| PH | 4.5 (0.1g/l, H2O) |
| umsebenzi wamehlo | [α]20/D +91±2°, c = 1% kwi-0.1 M NaOH |
| Ukunyibilika kwamanzi | Inyibilika emanzini ashushu, idimethyl sulfoxide, utywala kunye nebenzene. |
| Inovakalelo | Ukukhanya okunovelwano |
I-Biotin iyimfuneko ekukhuleni kweeseli, ukuveliswa kwee-acids ezinamafutha, kunye ne-metabolism yamafutha kunye ne-amino acids.Idlala indima kumjikelezo we-citric acid, okuyinkqubo apho amandla e-biochemical eveliswa ngexesha lokuphefumula kwe-aerobic.I-Biotin yi-coenzyme ye-carboxylase enzymes, ebandakanyeka kwi-synthesis ye-fatty acids, i-isoleucine, kunye ne-valine, kunye ne-gluconeogenesis.Ukongeza, i-biotin isetyenziswa ngokubanzi kulo lonke ishishini le-biotechnology ukudibanisa iiproteni zovavanyo lwe-biochemical.
Sidinga i-biotin malunga ne-100 ukuya kwi-300 micrograms ngosuku.Kukho iprotein yesibulala-zintsholongwane enokudibanisa ne-biotin kwiqanda elimhlophe.Emva kokudibanisa, ayinakuthatyathwa ngumzila wokugaya;kubangele ukunqongophala kwe-biotin yezilwanyana, kwangaxeshanye ukulahlekelwa ngumdla, i-glossitis, i-dermatitis dermatitis, ukususwa kweenwele njalo njalo.Nangona kunjalo, akukho meko yokunqongophala kwe-biotin emntwini, mhlawumbi ngenxa yokuba ukongeza kwimithombo yokutya, iibhaktheriya zamathumbu nazo zinokudibanisa i-biotin.I-Biotin yi-coenzyme yee-enzyme ezininzi emzimbeni womntu.Ithatha inxaxheba kwi-metabolism ye-aliphatic acid, i-carbohydrate, i-vitamin B12, i-folic acid kunye ne-pantothenic acid;ukukhuthaza ukuhlanganiswa kweprotheyini kunye ne-urea, kunye nokukhuthaza ukukhutshelwa.
Uncedo lwamafutha, i-glycogen kunye ne-amino acids kwi-synthesis eqhelekileyo kunye ne-metabolism emzimbeni womntu;
Ukukhuthaza ukusebenza okuqhelekileyo kunye nokukhula kwamadlala okubila, izicubu zemithambo-luvo, umongo wethambo, i-gonads yamadoda, ulusu kunye neenwele, kunye nokunciphisa i-eczema, iimpawu ze-dermatitis;
Ukuthintela ukulahleka kweenwele ezimhlophe kunye neenwele, igalelo kunyango lwempandla;
Ukuphelisa iintlungu zemisipha;
Ukukhuthaza ukuhlanganiswa kunye nokukhutshwa kwe-urea, i-purine synthesis kunye ne-oleic acid biosynthesis;
Kunyango lwe-atherosclerosis, i-stroke, i-dyslipidemia, uxinzelelo lwegazi, isifo sentliziyo kunye nokuphazamiseka kokujikeleza kwegazi.
