5-Fluoro-2′-deoxyuridine Cas: 50-91-9
| Inombolo Yekhathalogu | XD90578 |
| Igama lemveliso | 5-Fluoro-2'-deoxyuridine |
| CAS | 50-91-9 |
| Ifomula yeemolekyuli | I-C9H11FN2O5 |
| Ubunzima beMolekyuli | 246.19 |
| Iinkcukacha zokuGcina | 2 ukuya ku-8 °C |
| IKhowudi yoMrhumo eHarmonized | 29349990 |
Ukucaciswa kweMveliso
| Imbonakalo | Imhlophe ukuya kumgubo omhlophe wekristale |
| Isivavanyi | 99% |
| Ilahleko ekomisweni | ≤0.5% |
Ukukwazi kweClostridium thermocellum ukuthoba ngokukhawuleza iselulosi kunye nokubilisa okukhokelela kwimveliso ye-hydrolysis kwi-ethanol kuyenza ibe yindawo ethembisayo yeqonga lemveliso ye-cellulosic biofuel ngokudityaniswa kwe-bioprocessing.Okwangoku, nangona kunjalo, isivuno se-ethanol singaphantsi kakhulu kwethiyori ephezulu ngenxa yeendlela zemveliso ezinamagatsha eziphambukisa i-carbon kunye nee-electron ukuya kwi-formate, i-H2, i-lactate, i-acetate, kunye ne-amino acids efihliweyo.Ukuqondisa kwakhona i-carbon kunye ne-electron flux kude ne-formate, iijene ezifakwe kwi-pyruvate: i-formate lyase (pflB) kunye ne-PFL-activating enzyme (pflA) zacinywa.Imveliso yefomati kwisiphumo sohlobo lwe-Δpfl yapheliswa kwaye imveliso ye-acetate yehla nge-50% kuzo zombini eziyinkimbinkimbi kunye neziphakathi.Izinga lokukhula kohlobo lwe-Δpfl lwehle ngo-2.9-fold on defined medium and biphasic growth yabonwa kumbindi onzima.Ukongezwa kwendawo echaziweyo ene-2 mM ifomathi ebuyiselweyo Δpfl izinga lokukhula ukuya kwi-80 % yoxinzelelo lwabazali.Indima ye-pfl kubuchule bobunjineli be-metabolic kunye ne-C1 metabolism iyaxoxwa.
