o-Cresolphthalein Complexone CAS: 2411-89-4 powder omhlophe
Inombolo Yekhathalogu | XD90463 |
Igama lemveliso | o-Cresolphthalein Complexone |
CAS | 2411-89-4 |
Ifomula yeemolekyuli | I-C32H32N2O12 |
Ubunzima beMolekyuli | 636.62 |
Iinkcukacha zokuGcina | I-Ambient |
IKhowudi yoMrhumo eHarmonized | 2932209090 |
Ukucaciswa kweMveliso
Ilahleko ekomisweni | 7.23% |
Imbonakalo | Umgubo omhlophe |
Isivavanyi | 99% |
Ubushushu boGcino | +20 °C |
Ubunzima beMolekyuli | 636.6 |
Ukunyibilika | Sula isisombululo esimfusa |
Intsalela kwi-Ignition | 0.5% ubukhulu |
Nitrogen | 4.1-4.7% |
Lambda max | I-573nm kwi-0.1N i-sodium hydroxide |
Lamda Max | 575 (377) nm kwi-0.1 N sodium hydroxide |
Ikhabhoni | 58-63% |
Iiprotheni ze-Bone morphogenetic (BMPs) zidlala indima ephambili ekubunjweni kwamathambo kunye ne-cartilage.Kwezi zakhiwo, ii-BMPs ziqeshwe kwintsimi yobunjineli beethishu ukukhuthaza ukuvuselelwa kwamathambo kwizicubu ezonakalisiweyo.Ukoyisa imiqobo ngenxa yokusetyenziswa kweeproteni zizonke, iipeptides zokwenziwa ezivela kubazali bazo BMPs ziye zaphuma njengeemolekyuli ezithembisayo zoyilo lwebhayoloji.Kumhlaba wesakhiwo sovavanyo lwe-BMP-2 ye-receptor complexes echazwe kuncwadi, siyile iipeptides ezintathu, ukuvelisa kwakhona ummandla we-BMP-2 ojongene nokubophelela kuhlobo lwe-II receptor, i-ActRIIB.Ezi peptides ziphawulwe yi-NMR, kwaye iimpawu zesakhiwo se-peptide-receptor esibophelelayo ujongano zaye zabonakaliswa yi-docking experiments.I-Peptide-receptor binding affinities yahlalutywa ngokusebenzisa i-ELISA kunye neendlela ze-surface plasmon resonance.Ngapha koko, iimvavanyo zeselula zenziwa ukuvavanya iipropathi zabo ze-osteoinductive.I-peptide ye-chimera, efunyenwe ngokudibanisa i-ion port ion 73-92 kunye ne-30-34 ye-BMP-2, ibonisa ubudlelwane obuhle be-ActRIIB kuluhlu kwaye imele isiqalo esihle sokuyilwa kweekhompawundi ezintsha ezikwazi ukuvelisa iimpawu ze-osteogenic ze-osteogenic. umzali BMP-2.