Streptavidin evela Streptomyces avidinii CAS:9013-20-1
| Inombolo Yekhathalogu | XD90329 |
| Igama lemveliso | Streptavidin evela Streptomyces avidinii |
| CAS | 9013-20-1 |
| Ifomula yeemolekyuli | I-C14H17BrClNO2S |
| Ubunzima beMolekyuli | 378.71 |
| Iinkcukacha zokuGcina | -15 ukuya -20 °C |
| IKhowudi yoMrhumo eHarmonized | 35040090 |
Ukucaciswa kweMveliso
| Imbonakalo | Umgubo omhlophe |
| Isivavanyi | 99% |
| Isetyenziselwa uphando kuphela, hayi ukusetyenziswa komntu | uphando lusetyenziselwa kuphela, kungekhona ukusetyenziswa komntu |
I-Alkyne-hinged 3-fluorosialyl fluoride (DFSA) equlathe iqela le-alkyne iboniswe njengendlela-based target-specific irreversible inhibitor ye-sialidase.I-ester-protected analog DFSA (PDFSA) yi-membrane-permeable precursor ye-DFSA eyenzelwe ukusetyenziswa kwiiseli eziphilayo, kwaye yaboniswa ukwenza i-covalent adducts kunye ne-virus, ibhaktheriya, kunye ne-sialidases yabantu.I-adduct ye-fluorosialyl-enzyme inokudityaniswa ne-azide-annexed biotin ngokucofa ukusabela kwaye ibonwe yi-streptavidin-specific reporting signals.I-Liquid chromatography-mass spectrometry/mass spectrometry uhlalutyo kumaqhekeza e-tryptic peptide ibonisa ukuba i-3-fluorosialyl moiety ilungisa iintsalela zetyrosine ze-sialidase.I-DFSA yayisetyenziselwa ukubonisa usulelo lomkhuhlane kunye nokufunyaniswa kokuchaphazeleka kwentsholongwane kwi-anti-influenza drug oseltamivir acid, ngelixa i-PDFSA yayisetyenziselwa umfanekiso we-situ wotshintsho lomsebenzi we-sialidase kwiiseli eziphilayo.
